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Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor superfamily of ligand-dependant transcription factors which have been shown to alter during CKD and CVD [57-59]

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Within the framework of MASLD and ALD, the dysregulation of β-oxidation, in conjunction with an overloaded tricarboxylic acid (TCA) cycle, results in the production of excessive nicotinamide adenine dinucleotide (reduced form) (NADH)