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In studies involving inflammatory bowel disease (IBD), the peptide has been shown to mitigate intestinal inflammation, reduce lesion size, and promote the regeneration of the epithelial lining

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Under physiological conditions, cellular redox buffers [GSH/GSSG and NAD(P)H/NAD(P) + ] have sufficient capacity (termed basal redox buffer capacity [ReBC]) to maintain cellular oxidants and reductants at physiological levels (ROS as signaling molecules) (Fig