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470 In this study, researchers randomized 529 patients with heart failure with a preserved ejection fraction and body mass index (weight in kilograms in the square of the height in meters) ≥30 to receive once-weekly injections of semaglutide (2.4 mg) or placebo for 52 weeks

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Other preclinical studies suggest that similar doses may induce mild anxiolytic effects (23, 24) which could be beneficial to motivated behavior