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123 Vps34 lactylation at K356 and K781 enhances its interaction with Beclin1, Atg14L, and UVRAG and then increases Vps34 lipid kinase activity, thereby promoting autophagic flux and endolysosomal trafficking

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Additional markers to consider: oxidative stress markers (8-isoprostane, malondialdehyde), inflammatory markers (hsCRP, IL-6), liver function tests