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f , Quantification of the intestinal nuclei is based on their morphology, as depicted in ( e )

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The acute risks cluster around four effects: Hypoglycemia: IGF-1 is structurally similar to insulin, binds with low affinity to insulin receptors, suppresses hepatic glucose production, and stimulates peripheral glucose utilization, with hypoglycemia risk concentrated in the first month of treatment, according to Drugs.com in 2025