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Gut microbiome and its associations with acute and chronic gastrointestinal toxicities in cancer patients with pelvic radiation therapy: a systematic review

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By accumulating in the mitochondria and interfering with the electron transport chain, MPs cause damage to the membrane of this organelle and ultimately cause the production of free radicals, which in turn endanger the antioxidant defense reservoir, lipid peroxidation, protein oxidation and DNA damage (Fig