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Those SNPs, polymorphisms that are not located near any known genes, map to a region that displays significant evolutionary conservation and that may contain transcription factor binding sites or encode transcripts that are involved in the trans -regulation of the transcription of distant genes or the regulation of not yet identified genes

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2 (see HealthLink BC’s page on Quick Nutrition Check for Vitamin B 12 for dietary information).The prevalence of B 12 deficiency in the general population differs between older and younger people