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In addition, when neural dysfunction occurs, the increase of excitatory neurotransmitters such as glutamate can promote the influx of calcium ions and thus induce mitochondrial toxicity, leading to oxidative stress [13]

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62 Overall, the evidence shows that NAC, at a dose of 1800 mg per day on days 3−7 of the menstrual cycle, is beneficial as an add-on for women with PCOS who are undergoing fertility treatment with an ovulation-stimulating drug, such as CC