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Rather than a single threshold, concerning patterns include: creatinine rising above your established baseline on multiple measurements, creatinine rising progressively over months to years even if still within the normal range, creatinine above the upper limit of normal for your sex, or eGFR below 60 on two or more measurements separated by at least three months

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Injectable levocarnitine is dosed by a clinician based on the condition being treated, often several times weekly or, for dialysis patients, after sessions