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It has been suggested that in successfully aging individuals, there is a balance between pro-inflammatory stimuli (inflammaging)—such as interleukins IL-15, IL-18, IL-6, serum-amyloid A, fibrinogen, C reactive protein (CRP), von Willebrand factor, resistin, and leukotrienes [2,3,4]—and anti-inflammatory stimuli, such as adiponectin, the arachidonic acid cascade (cytochrome p450), IL-1 receptor antagonist (IL-1RA), and soluble tumor necrosis factor receptor (STNF-R) [5,6,7]

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