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And a cell-based bioassay, receptor autophosphorylation or a proliferation readout in a responsive line, is the only method that answers the question you actually care about, which is whether the molecule works

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Research peptides in this space fall into two distinct mechanistic categories: GHRH analogs (e.g., CJC-1295, Sermorelin, Tesamorelin ) — bind the GHRH receptor on pituitary somatotrophs to directly stimulate GH synthesis and release GHRPs / Ghrelin mimetics (e.g., Ipamorelin, GHRP-2, GHRP-6, Hexarelin) — bind the GHS-R1a receptor to amplify GH release through a separate, complementary pathway Ipamorelin falls firmly in the GHRP/ghrelin mimetic category