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Delete MS-DRGs 338 through 340 (Appendectomy with Complicated Principal Diagnosis with MCC, with CC, and without CC/MCC, respectively) and MS-DRGs 341 through 343 (Appendectomy without Complicated Principal Diagnosis with MCC, with CC, and without CC/MCC, respectively) describing appendectomy with and without a complicated principal diagnosis and create proposed new MS-DRGs 397, 398, and 399 (Appendix Procedures with MCC, with CC, without CC/MCC, respectively)

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found that berberine can increase the levels of neuroprotective factors, such as p-AKT and p-CREB, and down-regulate inflammatory response factors to inhibit inflammation, such as NF-κB (Zhang et al., 2012)